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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Orexin A alleviates neuroinflammation via OXR2/CaMKKβ/AMPK signaling pathway after ICH in mice

Fig. 3

Short-term outcome studies at 24 h after ICH. a Garcia test, b forelimb placement test, and c corner turn test at 24 h all showed that the neurological function were significantly decreased after ICH. Low dose (20 ng/μl) OXA administration failed to change the results; medium (60 ng/μl) and high dose (200 ng/μl) OXA treatment significantly improved the neurological outcomes; however, no significance was observed between the two groups. Kruskal-Wallis test with the Bonferroni correction, *p < 0.05 vs. sham group, #p < 0.05 vs. vehicle group. Error bars represent the means ± SD, n = 6 per group. d Hematoma volume was quantitatively estimated. It was significantly elevated after ICH; however, there was no significant differences between all the groups. Kruskal-Wallis test with the Bonferroni correction, *p < 0.05 vs. sham group. Error bars represent mean ± SD, n = 6 per group

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