Fig. 1

Change of sensorimotor functions and brain infarct volume after ischemic stroke in rats. Neurological functional change after MCAO in rats as shown in Longa test (a). Sensorimotor functional change after MCAO in rats as evaluated by adhesive removal test (b, c), Limb-use asymmetry test (cylinder) (d) and modified grip-traction test (e). Change of brain infarct volume after MCAO was assessed by cresyl violet staining (f, g). n = 8–15, results are expressed as means ± SEM. ^###P < 0.001, ^##P < 0.01, ^#P < 0.05 versus the Sham group. ^***P < 0.001, ^**P < 0.01, ^*P < 0.05 versus the 4 days MCAO group