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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: The CD200/CD200R signaling pathway contributes to spontaneous functional recovery by enhancing synaptic plasticity after stroke

Fig. 3

CD200R was transiently upregulated after ischemic stroke in rats. Representative western blots of CD200, CD200R, and their corresponding normalized control β-actin in ipsilateral sensorimotor cortex at 4 days, 7 days, and 28 days after MCAO (a, c). The levels of CD200R was upregulated at 4 days after MCAO, but MCAO did not influence the expression of CD200 at each time point (b, d). CD200R (red) staining showed protein expression at 4 days and colocalized with Iba1+(green) cells (Iba1: a microglia marker) after MCAO in ipsilateral sensorimotor cortex (e) (n = 3, Scale bar: 20 μm). Results are expressed as means ± SEM. ###P < 0.001, ##P < 0.01, #P < 0.05 versus the Sham group

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