Fig. 4

CD200/CD200R pathway contributed to functional recovery after ischemic stroke in rats. Sensorimotor functions were detected by Longa test (a), adhesive removal test (b, c), limb-use asymmetry test (cylinder) (d), and modified grip-traction test (e) after CD200Fc or CD200R Ab i.c.v injection, n = 8–15. The sizes of cerebral infarction were detected by cresyl violet staining (f, g), n = 7. Results are expressed as means ± SEM. ^###P < 0.001, ^##P < 0.01, ^#P < 0.05 versus the Sham group. ^***P < 0.001, ^**P < 0.01, ^*P < 0.05 versus the MCAO+IgG group