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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: TDAG8 deficiency reduces satellite glial number and pro-inflammatory macrophage number to relieve rheumatoid arthritis disease severity and chronic pain

Fig. 8

Histology of ipsilateral side joints stained with macrophage markers in compound-treated RA mice. Histology of joints from vehicle- or compound-treated mice at week 12 incubated with CD68 (b), CD80 (c), or CD163 (d) antibodies. Synovial sublining regions are shown in a. Magnification of × 40. The cell density (cells/mm2) was calculated and presented in histograms representing the mean ± SEM (b, c, d). *p < 0.05, **p < 0.01 compound- vs vehicle-treated group by one-way ANOVA. Yellow arrows are labeled cells

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