Fig. 3

Inhibition of CX3CR1 improves systolic blood pressure and NO production. a Time course of systolic blood pressure after intracerebroventricular administration of the CX3CR1 inhibitor AZD8797 for 2 weeks. b The bar graph presents NO concentration as micromoles nitrate per microgram of the NTS protein. One-way ANOVA with Scheffe’s post-hoc was performed for statistical analysis. The values are represented as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 compared to the control group. #P < 0.05, ##P < 0.01 compared to fructose-fed rats (n = 6~8 per group)