Fig. 4

CX3CR1 inhibits the Akt-nNOS pathway in the NTS of fructose-fed hypertensive rats. a Semi-quantitative immunoblot analysis determined the phosphorylation level of ERK1/2, Akt, nNOS, and eNOS protein in the NTS of fructose-fed rats. b The bar graph shows phosphorylated ERK1/2^T202/Y204, Akt^S473, nNOS^S1416_, and eNOS^S1177 in the NTS of hypertensive rats. One-way ANOVA with Scheffe’s post-hoc was performed for statistical analysis. The values are represented as mean ± SEM. *P < 0.05 compared to the control group. ^#P < 0.05 compared to fructose-fed rats(n = 6~8 per group)