Table 1 General characteristics of the fructose-induced WKY rats

Systolic blood pressure, mmHg

109.8 ± 1.8

125.1 ± 2.2***

144.5 ± 1.1***

Fasting serum glucose, mg/dL

85.3 ± 1.8

134.2 ± 4.9***

147.0 ± 4.0***

Fasting serum triglyceride, mg/dL

82.7 ± 1.2

155.3 ± 18.6***

177.8 ± 26.6***

Fasting serum dHDL, mg/dL

83.0 ± 1.6

75.5 ± 4.5*

71.5 ± 2.5*

Serum IL-1β, pg/mL

27.93 ± 5.13

49.97 ± 8.59*

74.90 ± 7.07*

Serum IL-6, pg/mL

3.44 ± 0.46

6.21 ± 0.24*

10.02 ± 1.69*

Serum TNF-α, pg/mL

25.82 ± 9.05

74.06 ± 5.62*

202.10 ± 17.82*

Serum fractalkine, ng/mL

0.38 ± 0.06

0.36 ± 0.04

0.43 ± 0.05

CSF fractalkine, ng/mL

1.20 ± 0.04

1.49 ± 0.07*

1.65 ± 0.03*

NTS fractalkine, ng/mg

4.06 ± 0.17

4.80 ± 0.36*

5.98 ± 0.38*

NTS IL-1β, pg/mg

6.53 ± 0.27

9.17 ± 0.32*

12.63 ± 0.83*

NTS IL-6, pg/mg

61.13 ± 6.30

115.48 ± 3.30*

150.87 ± 11.68*

NTSTNF-α, pg/mg

1.15 ± 0.24

4.67 ± 0.75*

12.17 ± 0.41*