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Table 2 General characteristics of the fructose-induced WKY rats and AZD8797-treated group

From: CX3CR1-microglia mediates neuroinflammation and blood pressure regulation in the nucleus tractus solitarii of fructose-induced hypertensive rats

Parameter/group

V-control

V-fructose

Fru-AZD8797

NTS fractalkine, ng/mg

5.33 ± 0.43

8.07 ± 0.29*

9.52 ± 0.66#

NTS IL-1β, pg/mg

4.83 ± 0.16

6.93 ± 0.20*

4.73 ± 0.13#

NTS IL-6, pg/mg

63.58 ± 4.32

76.87 ± 1.34*

49.70 ± 2.14#

NTSTNF-α, pg/mg

8.16 ± 0.78

21.63 ± 2.06*

14.16 ± 0.65#

  1. The values of quantitative ELISA of NTS areas for FKN, IL-1β,IL-6, and TNF-α are presented as mean ± SEM. One-way ANOVA with Scheffe’s post-hoc was performed for statistical analysis.
  2. *P < 0.05 vs control group (n = 6), #P < 0.05 vs fructose group (n = 6~8 per group)
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Journal of Neuroinflammation

ISSN: 1742-2094