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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Evaluation of M2-like macrophage enrichment after diffuse traumatic brain injury through transient interleukin-4 expression from engineered mesenchymal stromal cells

Fig. 9

Transcriptomic analysis of mouse brains local to site of intervention at 1 and 3 weeks. a Volcano plots demonstrating that IL-4 MSCs induced the most alterations in gene expression. Each graph presents genes of the latter condition vs. the former condition. b Select significantly over-represented pathways identified through g:Profiler and reported in S. Table 1. c Select significantly enriched pathways identified through Gene Set Enrichment Analysis and Molecular Signatures Database v7.0, Collection C5, reported in S. Table 2. d A heatmap presenting a selection of genes up- or downregulated compared to the Sham group

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Journal of Neuroinflammation

ISSN: 1742-2094