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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: 27-Hydroxycholesterol contributes to cognitive deficits in APP/PS1 transgenic mice through microbiota dysbiosis and intestinal barrier dysfunction

Fig. 3

The plasma levels and brain levels of 27-OHC (a), plasma Aβ1-40 and Aβ1-42 (b), brain Aβ1-40 and Aβ1-42 (c), brain TNF-α (d), and IL-17 (e) in C57BL/6J mice for different doses of 27-OHC treatment. One-way analysis of variance (ANOVA) was performed and post hoc comparisons were carried out using the LSD test. Asterisks indicate significant differences. Data are presented as mean ± SEM. n = 10/group. *P < 0.05; **P < 0.01

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