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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Tanshinone IIA alleviates brain damage in a mouse model of neuromyelitis optica spectrum disorder by inducing neutrophil apoptosis

Fig. 2

TSA administration inhibits the loss of myelination in NMOSD lesions at 24 h after brain injection. a Representative immunofluorescence staining of MBP. Lower magnification: top. Higher magnification: bottom. Yellow line, needle tract; white lines delimit the lesion. b Quantification of the extent of demyelination is expressed as the absolute reduction in area (mm2) of MBP in NMOSD lesions. Vehicle, n = 15; pre-TSA, n = 15; post-TSA, n = 5. *p < 0.05, ***p < 0.001. The data are representative of three independent experiments. One-way ANOVA followed by Tukey’s multiple comparison tests was performed

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Journal of Neuroinflammation

ISSN: 1742-2094