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Table 4 Body weights of embryos and dams and the chow intake and litter size of dams

From: CCL2/CCR2 system in neuroepithelial radial glia progenitor cells: involvement in stimulatory, sexually dimorphic effects of maternal ethanol on embryonic development of hypothalamic peptide neurons

Ethanol
  Untreated Control Ethanol
 Body weight—E19 (g) 6.670 ± 0.39 6.120 ± 0.16 6.310 ± 0.19
 Body weight—dams (g) 295.5 ± 8.5 285.0 ± 12.3 282.1 ± 10.3
 Chow intake (kcal/day) 71.90 ± 2.9 70.70 ± 3.2 65.40 ± 3.4
 Litter size 11.70 ± 1.0 12.40 ± 0.7 12.70 ± 0.6
CCL2
  Untreated Control CCL2
 Body weight—E19 (g) 6.200 ± 0.28 6.000 ± 0.17 6.040 ± 0.18
 Body weight—dams (g) 292.1 ± 7.4 277.3 ± 5.0 279.1 ± 6.5
 Chow intake (kcal/day) 66.70 ± 4.1 68.40 ± 3.2 64.10 ± 4.4
 Litter size 11.70 ± 1.2 12.40 ± 0.7 12.70 ± 0.6
Ethanol + INCB
  Control Ethanol Ethanol + INCB3344
 Body weight—E19 (g) 6.290 ± 0.23 6.070 ± 0.23 6.160 ± 0.13
 Body weight—dams (g) 280.3 ± 8.7 273.9 ± 11.0 282.7 ± 9.1
 Chow intake (kcal/day) 75.30 ± 4.7 72.20 ± 3.0 69.50 ± 2.7
 Litter size 11.30 ± 1.0 11.60 ± 1.3 11.00 ± 1.2
  1. Data are mean ± SEM. n = 7/group, *p < 0.05 versus control. Two-way ANOVA was used to compare means between groups and showed no significant effect of maternal administration of ethanol, CCL2 or CCR2 antagonist, INCB3344, on these measures
  2. kcal/day kilocalories per day, g grams, INCB3344 CCR2 antagonist