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Table 7 Effects of ethanol on density of cells or processes that label CCL2, BLBP, NeuN, or Iba-1 in NEP and mHYP

From: CCL2/CCR2 system in neuroepithelial radial glia progenitor cells: involvement in stimulatory, sexually dimorphic effects of maternal ethanol on embryonic development of hypothalamic peptide neurons

Labeled cells/processes Location Control (cells, objects/μm2) Ethanol (cells, objects/μm2)
CCL2+ NEP 6.30E− 5 ± 2.67E− 6 7.50E− 5 ± 2.07E− 6*
mHYP 9.90E− 5 ± 7.30E− 6 1.70E− 4 ± 1.46E− 5*
BLBP+ NEP 1.51E− 4 ± 4.62E− 6 1.83E− 4 ± 5.67E− 6*
mHYP 1.59E− 4 ± 1.32E− 5 2.31E− 4 ± 2.13E− 5*
NeuN+ NEP 5.75E− 5 ± 2.77E− 6 7.92E− 5 ± 7.24E− 6*
mHYP 4.28E− 5 ± 2.68E− 6 5.17E− 5 ± 2.64E− 6*
Iba-1+ NEP 3.79E− 5 ± 1.84E− 6 4.73E− 5 ± 1.79E− 6*
mHYP 4.47E− 5 ± 2.14 E− 6 6.06E− 5 ± 4.27E− 6*
  1. Maternal administration of ethanol (2 g/kg/day, E10–E15) was compared to an isocaloric maltose-dextrin control solution (Control) group in the NEP and mHYP areas of female E19 embryos, measured using single-labeling IF. Data are mean ± SEM, n = 6/group, *p < 0.05 versus Control. The difference between groups was analyzed using Student t test
  2. BLBP brain lipid-binding protein, CCL2 C-C motif ligand 2, Iba-1 microglial marker, mHYP medial hypothalamus, NEP hypothalamic neuroepithelium, NeuN neuronal marker