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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Lipocalin 2 induces neuroinflammation and blood-brain barrier dysfunction through liver-brain axis in murine model of nonalcoholic steatohepatitis

Fig. 8

a Co-localization and morphometric analysis of NLRP3 reactivity with astrocytes, microglia, neurons, and brain endothelial cells marked as NLRP3/GFAP, NLRP3/CD11b, NLRP3/NeuN, and NLRP3/CD31 respectively in brain slices from MCD fed mouse group. Co-localization was displayed yellow dots in a, highlighted by white circles. Images were taken at × 40. b Immunoreactivity of co-localization was displayed by yellow dots in a, and immunoreactivity was displayed as bar graph representing mean ± SD of ROI % of 3 different areas (n = 3). Significance was tested between the groups by unpaired t test, *p < 0.05, **p < 0.01, ***p < 0.001

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