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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Histamine 2/3 receptor agonists alleviate perioperative neurocognitive disorders by inhibiting microglia activation through the PI3K/AKT/FoxO1 pathway in aged rats

Fig. 3

An agonist of H2R or H3R inhibits microglia activation and TLR4 expression in rat hippocampus. Immunofluorescent staining was used to detect Iba1 (red) and TLR4 (green) in hippocampal CA1 region. Blue staining represents DAPI. Scale bar = 50 μm. Histogram represents the quantification of Iba1 and TLR4 positive cells in the hippocampal CA1 area. **P < 0.01 versus the control group. #P < 0.05 versus the surgery group (n = 4). The data are presented as the mean ± SEM

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Journal of Neuroinflammation

ISSN: 1742-2094