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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Histamine 2/3 receptor agonists alleviate perioperative neurocognitive disorders by inhibiting microglia activation through the PI3K/AKT/FoxO1 pathway in aged rats

Fig. 4

An agonist of H2R or H3R inhibits exploratory laparotomy-induced inflammatory factor production in rat hippocampus. The levels of the proinflammatory factors TNF-ɑ, IL-Iβm and IL-10 were detected by ELISA. **P < 0.01 versus the control group. #P < 0.05, ##P < 0.01 versus the surgery group (n = 4). The data are presented as the mean ± SEM

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Journal of Neuroinflammation

ISSN: 1742-2094