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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Histamine 2/3 receptor agonists alleviate perioperative neurocognitive disorders by inhibiting microglia activation through the PI3K/AKT/FoxO1 pathway in aged rats

Fig. 5

LPS induced downregulation of H2R and H3R expression in microglia. a The protein levels of H2R, H3R, and TLR4 were detected in primary cultured microglia by Western blotting using specific antibodies. b–d Expression of H2R, H3R, and TLR4 was quantified and normalized to β-actin levels. Each value was expressed relative to that in the control group (0 h), which was set to 100. **P < 0.01 versus the control group (n = 3). The data are presented as the mean ± SEM

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Journal of Neuroinflammation

ISSN: 1742-2094