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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: A1 reactive astrocytes and a loss of TREM2 are associated with an early stage of pathology in a mouse model of cerebral amyloid angiopathy

Fig. 4

Dysregulation of immune response and lipid processing network in Tg-FDD mice. a Heatmap of gene expression (red = upregulation, blue = downregulation) and b network analysis of significantly affected genes determined by RNA-Seq in WT versus Tg-FDD mice (n = 3; 9-month-old). c Bolded genes from lipid processing and immune response network indicate genetic association with LOAD or if the gene has been nominated as a potential target for AD. logFC, log2 (fold change); FDR, false discovery rate

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Journal of Neuroinflammation

ISSN: 1742-2094