Fig. 7From: NF-κB p65-dependent transcriptional regulation of histone deacetylase 2 contributes to the chronic constriction injury-induced neuropathic pain via the microRNA-183/TXNIP/NLRP3 axisMechanism graph of NF-κB p65-mediated HDAC2 in CCI-induced neuropathic pain. NF-κB p65-activated HDAC2 could induce inflammation reaction to aggravate neuropathic pain in CCI rats by downregulating miR-183 and promoting TXNIP and NLRP3Back to article page