Fig. 1

Experimental outline of HFD protocol on the dams and the offspring. Diet protocol period is identified by a pale blue-colored bar on the dams and the offspring timelines. At PND21, all offspring were on normal chow diet before sacrifice at PND30. Part of the animals received an intraperitoneal LPS injection 8 h before characterizing their peripheral inflammatory profile. ♀, female; ♂, male; E, embryonic days; LPS, lipopolysaccharide; P, postnatal days; SAL, saline; W, weeks