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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Ingestion of Lactobacillus intestinalis and Lactobacillus reuteri causes depression- and anhedonia-like phenotypes in antibiotic-treated mice via the vagus nerve

Fig. 3

Altered composition in the gut microbiota at the species level. a The relative abundances of species in fecal samples of the four groups 24 h after the final FMT. b Akkermansia muciniphila (two-way ANOVA, antibiotic: F1,24 = 6.721, P = 0.016; FMT: F1,24 = 0.107, P = 0.746; interaction: F1,24 = 0.963, P = 0.336). c [Clostridium] cocleatum (two-way ANOVA, antibiotic: F1,24 = 6.153, P = 0.021; FMT: F1,24 = 2.733, P = 0.111; interaction: F1,24 = 16.133, P = 0.001). d Lactobacillus intestinalis (two-way ANOVA, antibiotic: F1,24 = 1.753, P = 0.198; FMT: F1,24 = 1.830, P = 0.189; interaction: F1,24 = 13.700, P = 0.001). e Lactobacillus reuteri (two-way ANOVA, antibiotic: F1,24 = 0.298, P = 0.590; FMT: F1,24 = 1.154, P = 0.293; interaction: F1,24 = 6.966, P = 0.014). Data are shown as mean ± S.E.M. (n = 7). *P < 0.05, **P < 0.01, ***P < 0.001. FMT fecal microbiota transplantation, NS not significant, W + FMT-C water + FMT from control (no CSDS) mice, W + FMT-S water + FMT from CSDS-susceptible mice, A + FMT-S antibiotic + FMT from CSDS-susceptible mice, A + FMT-C antibiotic + FMT from control (no CSDS) mice

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