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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: FGF21 alleviates neuroinflammation following ischemic stroke by modulating the temporal and spatial dynamics of microglia/macrophages

Fig. 5

Effects of rhFGF21 on peripheral immune cells in the spleen at day 3 after MCAO in mice. a Representative gating strategy of neutrophils (CD11b+Ly6G+), monocytes (CD11b+Ly6C+), CD8+ T cells, CD4+ cells, NK1.1+ cells, and macrophages (CD11b+F4/80+) in a single-cell suspension from the spleen using FMO control samples. b Cumulative data for quantifying the percentage of the above immune cell subsets. c Gating strategy of CD68, CD86, and CD206 expressed in macrophages from the spleen 3 days after stroke. d Bar graph shows the percentage of CD68+, CD86+, and CD206+ cells in macrophages. n = 6 in the sham group, n = 10 in the MCAO and rhFGF21-treated group. Values are mean ± SEM by one-way ANOVA

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