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Table 1 The effect of MIA induced by LPS and Poly I:C treatment on the gene expression of Cx3cl1, Cx3cr1, Cd200 and Cd200r in the hippocampi (Hp) and the frontal cortices (Cx) of offspring at PND7. The mRNA levels were measured using qRT-PCR with n = 6–8 in each group. The results are presented as the average fold change ± SEMs

From: The prenatal challenge with lipopolysaccharide and polyinosinic:polycytidylic acid disrupts CX3CL1-CX3CR1 and CD200-CD200R signalling in the brains of male rat offspring: a link to schizophrenia-like behaviours

Factor Gene expression
Hp Cx Hp Cx
kLPS LPS kLPS LPS kPoly Poly kPoly Poly
Cx3cl1 1.01 ± 0.06 1.41 ± 0.17* 1.01 ± 0.07 1.09 ± 0.12 1.03 ± 0.12 0.92 ± 0.06 1.01 ± 0.06 0.90 ± 0.04
Cx3cr1 1.03 ± 0.09 1.31 ± 0.18 1.04 ± 0.10 0.98 ± 0.14 1.02 ± 0.09 1.06 ± 0.07 1.01 ± 0.06 0.88 ± 0.05
Cd200 1.00 ± 0.03 1.43 ± 0.19* 1.03 ± 0.11 1.21 ± 0.17 1.10 ± 0.23 0.89 ± 0.09 1.02 ± 0.10 0.73 ± 0.05*
Cd200r 1.07 ± 0.14 1.31 ± 0.18 1.09 ± 0.21 0.88 ± 0.26 1.09 ± 0.22 0.98 ± 0.15 1.06 ± 0.16 0.92 ± 0.06
  1. *p < 0.05 vs. appropriate control (kLPS or kPoly)