Factor
|
Gene expression
|
---|
Hp
|
Cx
|
Hp
|
Cx
|
---|
kLPS
|
LPS
|
kLPS
|
LPS
|
kPoly
|
Poly
|
kPoly
|
Poly
|
---|
M1-like phenotype
|
MhcII
|
1.03 ± 0.09
|
0.83 ± 0.06
|
0.98 ± 0.18
|
0.91 ± 0.11
|
1.02 ± 0.08
|
0.84 ± 0.12
|
1.17 ± 0.24
|
0.90 ± 0.11
|
Cd68
|
1.09 ± 0.07
|
1.44 ± 0.29
|
1.05 ± 0.13
|
1.02 ± 0.13
|
1.08 ± 0.18
|
0.76 ± 0.09
|
0.93 ± 0.03
|
0.81 ± 0.07
|
Cd40
|
1.01 ± 0.04
|
1.16 ± 0.14
|
0.97 ± 0.07
|
1.36 ± 0.14*
|
1.02 ± 0.09
|
0.92 ± 0.10
|
1.00 ± 0.04
|
0.80 ± 0.05*
|
iNos
|
0.96 ± 0.34
|
1.44 ± 0.21
|
0.92 ± 0.20
|
1.03 ± 0.21
|
0.81 ± 0.11
|
1.49 ± 0.26*
|
1.14 ± 0.21
|
1.21 ± 0.29
|
Il-1β
|
1.02 ± 0.08
|
1.79 ± 0.27*
|
1.02 ± 0.09
|
1.16 ± 0.12
|
1.04 ± 0.11
|
1.09 ± 0.07
|
1.03 ± 0.10
|
0.81 ± 0.05
|
Tnf-α
|
1.00 ± 0.03
|
1.63 ± 0.29*
|
1.02 ± 0.08
|
1.22 ± 0.14
|
1.08 ± 0.17
|
0.82 ± 0.06
|
1.04 ± 0.12
|
0.83 ± 0.07
|
Il-6
|
1.02 ± 0.08
|
1.24 ± 0.11
|
1.03 ± 0.10
|
1.20 ± 0.13
|
1.05 ± 0.11
|
0.92 ± 0.08
|
0.94 ± 0.12
|
1.37 ± 0.11*
|
M2-like phenotype
|
Arg1
|
1.01 ± 0.05
|
1.59 ± 0.25*
|
1.02 ± 0.08
|
1.19 ± 0.12
|
1.05 ± 0.13
|
0.94 ± 0.08
|
1.04 ± 0.13
|
0.95 ± 0.09
|
Igf-1
|
1.01 ± 0.06
|
0.94 ± 0.02
|
1.00 ± 0.03
|
0.98 ± 0.06
|
1.03 ± 0.10
|
1.28 ± 0.09
|
1.02 ± 0.06
|
1.10 ± 0.05
|
Tgf-β
|
1.01 ± 0.05
|
1.64 ± 0.26*
|
1.08 ± 0.12
|
1.21 ± 0.09
|
1.03 ± 0.09
|
0.96 ± 0.06
|
1.02 ± 0.09
|
0.74 ± 0.04*
|
Il-4
|
1.05 ± 0.12
|
0.95 ± 0.11
|
1.21 ± 0.29
|
1.10 ± 0.25
|
1.03 ± 0.09
|
0.91 ± 0.10
|
Not detected
|
Not detected
|
Il-10
|
1.09 ± 0.18
|
1.77 ± 0.26*
|
0.86 ± 0.27
|
1.11 ± 0.19
|
1.04 ± 0.12
|
1.57 ± 0.21
|
1.06 ± 0.15
|
0.40 ± 0.07*
|
- *p < 0.05 vs. appropriate control (kLPS or kPoly)