Fig. 1

Inhibition of the type 1 IFN response has no effect on lifespan. a Kaplan-Meier survival curve of WT mice injected i.p. with PBS (n = 4) or 25 mg/kg CBE (n = 8) or MyTrMaSt null mice injected with PBS (n = 6) or 25 mg/kg CBE (n = 13). b RT-PCR from brain homogenates (day 96) of WT and MyTrMaSt null mice injected with PBS (n = 2) or CBE (25 mg/kg) (n = 4). Cycle threshold values were normalized to levels of hypoxanthine phosphoribosyltransferase 1 (HPRT1). * p < 0.05, ** p < 0.01