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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Mice defective in interferon signaling help distinguish between primary and secondary pathological pathways in a mouse model of neuronal forms of Gaucher disease

Fig. 2

Attenuated neuroinflammation in MyTrMaSt null mice. a mRNA levels in brain homogenates from 96–130-day-old CBE-injected mice (25 mg/kg; n = 6–11) and PBS injected mice (n = 4–6). RNA expression is shown as arbitrary units (AU). * p < 0.05. b A representative western blot from brain homogenates is shown (70 μg of protein) of 19-day-old WT or MyTrMaSt null mice injected with 100 mg/kg CBE or PBS from 8 days of age. Results are representative of 3 experiments for control mice and 5 for CBE-treated mice, which all gave similar results. Tubulin was used as loading control and was similar in each lane. Quantification is normalized to tubulin. *p < 0.05

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