Table 1 mRNA levels of genes encoding PRRs in brain homogenates from 18-day-old mice injected daily with 100 mg/kg body weight CBE from day 8

Tlr1

7.5 ± 1.4

< 0.001

Tlr2

17.3 ± 2.8

< 0.005

Tlr3

5.0 ± 1.4

< 0.005

Tlr4

4.1 ± 0.5

< 0.001

Tlr5

1.7 ± 0.6

n.s.

Tlr6

3.7 ± 2.0

n.s.

Tlr7

6 ± 1.8

< 0.001

Tlr8

3.8 ± 2.6

n.s.

Tlr9

2.4 ± 0.9

n.s.

Tlr11

1.3 ± 1.1

n.s.

Tlr12

1.1 ± 0.4

n.s.

Tlr13

9.1 ± 1.5

< 0.001

Rig-I

6.6 ± 1.5

< 0.005

Mda5

8.4 ± 2.3

< 0.005

Nod2

2.7 ± 0.8

< 0.05

cGAS

3.1 ± 0.6

0.005

Sting

2.8 ± 0.8

< 0.05