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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Microglial-associated responses to comorbid amyloid pathology and hyperhomocysteinemia in an aged knock-in mouse model of Alzheimer’s disease

Fig. 5

Spatial analysis of P2ry12 positive microglia near plaques in KI. Representative images of concentric, 30-μm width analysis regions are shown in a where P2ry12 staining is in red, 6E10 staining is in blue, and output of the analysis algorithm is shown in yellow. Total % positive area for P2ry12 is quantified in b, and average pixel intensity (AU) within each region shown in c. **p < .01, ***p < .005, ****p < .001 versus the inner ring within dietary groups. Two-way mixed measures ANOVA with Dunnett’s post hoc tests

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