Fig. 4

LGTV infection diminished anxiety-like behavior in wildtype mice. Uninfected control (WT: n = 10, Irf-7^−/−: n = 8) and LGTV-infected (10⁴ FFU, i.p.) mice (WT: n = 10, Irf-7^−/−: n = 9) were tested for 5 min in the elevated plus maze. a Activity percentage of mice in the closed arms (C) and open arms (O) of the elevated plus maze and b the number of entries to the open arms are shown. c Group mean heat maps of the animals’ center position are illustrated for all tested groups. One-way ANOVA and post hoc Student’s t test using Fisher’s least significant differences were employed to analyze the data. Data are shown as mean ± SEM, **p < 0.01