Fig. 6

STRING protein-protein interaction networks of immunosuppressive DEGs. STRING protein-protein interaction networks of upregulated (red) and downregulated (blue) DEGs directly associated with a CD24, b THBS1 and THBS2, and c CD276. The list of transcripts used to create these networks was derived from all DEGs associated with clusters 1, 2, and 4. Each node indicates a specific protein, shaded according to its log₂ fold change value (PEG vs. NC comparison). Pink = upregulated, blue = downregulated. Distances between nodes indicates greater or lesser association between proteins, while the thickness of the lines between nodes indicates the confidence score of the interaction (thicker = greater confidence, thinner = lesser confidence). The positions of CD24, THBS1, THBS2, and CD276 in each network are indicated by red borders