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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Impact of ambient temperature on inflammation-induced encephalopathy in endotoxemic mice—role of phosphoinositide 3-kinase gamma

Fig. 4

Marked increase of microglial cell activation due to LPS-induced SIRS in brains of mice kept under neutral Ta (a) and reduced Ta (b). The effect is exacerbated by reduced Ta in the wild-type mice, but not in the genetically modified animals. Values are presented as boxplots illustrating medians within boxes from first quartile to the third quartile and whiskers ranging from the 10th to the 90th percentiles (a, b: n = 4–6, at each group and experimental state. * § † p < 0.05, asterisk indicates significant differences versus baseline within each group, section sign indicates significant differences versus wild-type mice kept under same Ta, dagger sign indicates significant differences versus mice kept under neutral Ta at the same experimental state, two-way ANOVA, followed by Holm–Sidak test for post hoc multiple comparisons, each)

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