Fig. 5
Increased LPS-induced mRNA expression of MMP-2, MMP-3, MMP-9, and MMP-13 appeared 24 h post LPS mainly in brains obtained from PI3Kγ-deficient mice kept under reduced Ta. Values are presented as boxplots illustrating medians within boxes from first quartile to the third quartile and whiskers ranging from the 10th to the 90th percentiles (a–d, n = 5 per each group and experimental state. § † p < 0.05, section sign indicates significant differences versus wild-type mice kept under same Ta, dagger sign indicates significant differences versus mice kept under neutral Ta of the same genotype, two-way ANOVA, followed by Holm–Sidak test for post hoc multiple comparisons, each)