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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Ablation of polyamine catabolic enzymes provokes Purkinje cell damage, neuroinflammation, and severe ataxia

Fig. 1

Polyamine pathway and confirmation of loss of Smox and Sat1 expression in Smox/Sat1-dKO mice. a Schematic depiction of the polyamine metabolic pathway, as well as import and export mechanisms. The main pathways of polyamine catabolism that are facilitated by SMOX and SAT1 were disrupted in Smox/Sat1-dKO mice. b The expression of both Smox and Sat1 transcripts were absent in total RNA extracted from the cerebellum of Smox/Sat1-dKO mice

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