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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Role of sex and high-fat diet in metabolic and hypothalamic disturbances in the 3xTg-AD mouse model of Alzheimer’s disease

Fig. 6

Sex differences in hypothalamic gliosis in response to AD and HF diet. Labeling of tissue sections including the hypothalamus was performed for GFAP. Quantification was performed for percent area positive for each label in the arcuate nucleus (a), ventromedial nucleus (b), dorsomedial nucleus (c), paraventricular nucleus (d), and lateral hypothalamus area (e). Representative images for labeling with GFAP are also shown (f). N = 3–5/group. *** = diet effect p < 0.001; **** = diet effect p < 0.0001; $$$ = sex effect p < 0.001; $$$$ = sex effect p < 0.0001; ^^ = AD effect p < 0.01; ^^^ = AD effect p < 0.001; ^^^^ = AD effect p < 0.0001

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