Skip to main content
Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Molecular patterns from a human gut-derived Lactobacillus strain suppress pathogenic infiltration of leukocytes into the central nervous system

Fig. 4

HK Lb reduces CNS-infiltrating leukocytes. a The number of CD45+CD11b+ macrophages in the CNS of EAE-induced mice treated with vehicle (PBS), live Lb, or HK Lb (n = at least 4 mice per group) at 14 DPI. b The number of CD45+CD11b lymphocytes in the CNS of EAE-induced mice treated with PBS, live Lb, or HK Lb (n = at least 4 mice per group) at 14 DPI. c The number of CD45+ leukocytes in the spleen of EAE-induced mice treated with PBS or HK Lb (n = 4 mice per group) at 14 DPI. d Concentration of chemokines CCL3, CCL4, CXCL5, and CXCL13 in the plasma of EAE-induced mice treated with PBS or HK Lb (n = 5 mice per group) at 14 DPI. Data are presented as mean ± SEM. *P ≤ 0.05, **P ≤ 0.01. ns, not significant; one-way ANOVA with Tukey’s multiple comparisons test for a and b and Student t test for c and d

Back to article page