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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Molecular patterns from a human gut-derived Lactobacillus strain suppress pathogenic infiltration of leukocytes into the central nervous system

Fig. 7

Adoptive transfer of spleen and mesenteric lymph node leukocytes from HK Lb-treated mice does not protect against induced EAE. a EAE clinical scores and b incidence for adoptive transfer-naive C57BL/6 mice or mice receiving 108 leukocytes from either PBS-treated, EAE-induced donors or HK Lb-treated, EAE-induced donors at − 1 DPI (n = at least 4 mice per group). c Transferred CD45.1+ leukocytes and d endogenous CD45.2+ leukocytes in the CNS of recipient mice (n = 4 per group). e Endogenous CD45.2+ leukocytes and f transferred CD45.1+ leukocytes in the spleen of recipient mice (n = 4 per group). Data are presented as mean ± SEM. **P ≤ 0.01, ***P ≤ 0.001. ns, not significant; AUC one-way ANOVA Tukey’s multiple comparisons test for a, log-rank test for b, and one-way ANOVA Tukey’s multiple comparisons test for c to f

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