Associations between gut microbiota and Alzheimer’s disease, major depressive disorder, and schizophrenia

Table 1 Description of gut microbiota, metabolites, and neuropsychiatric disorders

Traits	Consortium or study	Sample size	Populations	Journal	Year
Gut
Gut microbiota	PopGen/FoCus	1812 individuals	European	Nat Genet.	2016
Gut metabolites	FHS	2076 individuals	European	Cell Metab.	2013
Neuropsychiatric disorders
Alzheimer’s disease	IGAP^a	25,580 cases and 48,466 controls	European	Nat Genet.	2013
Major depression disorder	PGC29/deCODE/GenScotland/GERA/iPSYCH/UK Biobank/23andMeD	135,458 cases and 344,901 controls	European	Nat Genet.	2018
Schizophrenia	Sweden/PGC	21,246 cases and 38,072 controls	European	Nat Genet.	2013

FoCus Food-Chain Plus, GERA Genetic Epidemiology Research on Adult Health and Aging, PGC Psychiatric Genomics Consortium
^a IGAP includes the Alzheimer’s Disease Genetics Consortium (ADGC), the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium (CHARGE), the European Alzheimer’s disease Initiative (EADI), and the Genetic and Environmental Risk in Alzheimer’s disease consortium (GERAD)

ISSN: 1742-2094