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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Evaluation of neurofilament light chain in the cerebrospinal fluid and blood as a biomarker for neuronal damage in experimental pneumococcal meningitis

Fig. 1

Effect of intracisternal puncture on NfL level. a Serum NfL levels of animals (n = 3) before any intervention and mock-infected animals at 18 hpi (n = 16) were similar. b At 42 hpi, mock-infected animals punctured a second time at 18 hpi (n = 7) demonstrated higher CSF NfL levels (p = 0.01), while there was only a trend for higher serum NfL levels (n = 8) compared to non-punctured animals at 18 hpi (CSF n = 7; serum n = 8). c In infected animals, second time punctured (CSF n = 6; serum n = 10) and not punctured animals (CSF n = 16; serum n = 17) displayed similar NfL levels both in CSF and serum at 42 hpi

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Journal of Neuroinflammation

ISSN: 1742-2094