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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Knockdown of long non-coding RNA SOX2OT downregulates SOX2 to improve hippocampal neurogenesis and cognitive function in a mouse model of sepsis-associated encephalopathy

Fig. 7

SOX2OT knockdown downregulated SOX2 and OCT4 in the hippocampus of mice with sepsis-associated encephalopathy. a Representative images showing SOX2 and OCT4 protein bands in hippocampal tissue from CLP mice injected with SOX2OT siRNA or scrambled control. b Densitometry quantitation of SOX2 and OCT4 expression. β-actin was used as an internal control. c Levels of SOX2OT, SOX2, and OCT4 transcripts (n = 8/group). **p < 0.01. Abbreviations: CLP, cecal ligation and perforation; si-CRTL, scrambled control siRNA; si-SOX2OT, SOX2OT siRNA

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Journal of Neuroinflammation

ISSN: 1742-2094