From: Air pollution as a contributor to the inflammatory activity of multiple sclerosis
Spearman’s Rho between mean of PM10 15 days before enrolment and: | Healthy Controls (n = 19) | MS patients (n = 57) | ||
---|---|---|---|---|
CD4 T cells | CD8 T cells | CD4 T cells | CD8 T cells | |
Activation markers | ||||
 CD69 | − 0.2, p = 0.58 | 0.22, p = 0.55 | 0.08, p = 0.66 | − 0.07, p = 0.70 |
 HLA DR3 | 0.22, p = 0.60 | 0.35, p = 0.40 | − 0.14, p = 0.53 | − 0.30, p = 0.18 |
 CD38 | 0.31, p = 0.45 | 0.36, p = 0.38 | 0.004, p = 0.99 | 0.01, p = 0.96 |
Adhesion and migration markers | ||||
 CD44 | 0.13, p = 0.6 | 0.45, p = 0.06 | 0.22, p = 0.1 | 0.23, p = 0.08 |
 VLA4 | − 0.05, p = 0.84 | 0.13, p = 0.6 | 0.17, p = 0.21 | 0.12, p = 0.36 |
 LFA1 | 0.02, p = 0.92 | 0.17, p = 0.5 | 0.26, p = 0.05 | − 0.11, p = 0.44 |
 CCR6 | − 0.02, p = 0.93 | − 0.22, p = 0.37 | 0.43, p = 0.001 | 0.23, p = 0.09 |
 CXCR3 | − 0.02, p = 0.94 | − 0.01, p = 0.96 | 0.10, p = 0.44 | 0.03, p = 0.83 |