Fig. 1

Tan IIA ameliorates learning and memory deficits in APP/PS1 mice. a Experimental design showing tan IIA administration in APP/PS1 mice and the behavioral tests. b–d Open-field test. Time spent in center b, number of central entries c, and relative distance in center d. e The percentage of spontaneous alternation in Y maze analysis. f–i Morris water maze test. Representative path tracings of each group during the navigation trials f, the escape latency g, the percentage of time spent in the target quadrant h, and the number of crossing through the platform i. n = 10. Data were presented as mean ± SD. ^#p < 0.05 or ^##p < 0.01 vs. WT group, and *p < 0.05 or **p < 0.01 vs. APP/PS1 group