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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Tanshinone IIA attenuates neuroinflammation via inhibiting RAGE/NF-κB signaling pathway in vivo and in vitro

Fig. 9

Tan IIA, FPS-ZM1, and Bay11-7082 attenuate the production of pro-inflammatory cytokines in Aβ1–42-stimulated BV2 and U87 cells. ac The mRNA expression of TNF-α a, IL-6 b, and IL-1β c in BV2 and U87 cells were detected by qRT-PCR. df The protein expression of TNF-α d, IL-6 e, and IL-1β f in BV2 and U87 cells were measured by ELISA. n = 3. Data are presented as mean ± SD. #p < 0.05 or ##p < 0.01 vs. control, and *p < 0.05 or **p < 0.01 vs. Aβ1–42 treated cells

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