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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: RAM-589.555 favors neuroprotective and anti-inflammatory profile of CNS-resident glial cells in acute relapse EAE affected mice

Fig. 3

RAM-589.555 accesses the CNS: pharmacokinetic analysis of RAM-589.555 in plasma and brain of EAE mice. The plasma (a) and CNS (b) concentration-time profiles of RAM-589.555 following 25 mg/kg oral dose in mice displaying EAE (results for pharmacokinetic analysis of RAM-589.555 in healthy are shown in Additional file 4). Symbols indicate the observed plasma and CNS concentrations (n = 4 per time point). The data presented are the mean ± SEM according to three independent experimental repeats

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Journal of Neuroinflammation

ISSN: 1742-2094