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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: RAM-589.555 favors neuroprotective and anti-inflammatory profile of CNS-resident glial cells in acute relapse EAE affected mice

Fig. 5

RAM-589.555 does not modulate the secretion of BDNF, GDNF, and FGF2 from activated microglia and astrocytes. LPS-activated microglia and TNFa-activated astrocytes were cultured in the absence or presence of RAM589.555 at 25–400 nM for 48 h. Levels of BDNF (a), GDNF (b), and FGF2 (c) were measured in supernatants by ELISA. Error bars represent ± SEM according to three independent experimental repeats (duplicate/experiment)

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Journal of Neuroinflammation

ISSN: 1742-2094