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Table 1 EAE score following treatment with RAM-589.555

From: RAM-589.555 favors neuroprotective and anti-inflammatory profile of CNS-resident glial cells in acute relapse EAE affected mice

Treatment

No. of mice

Peak of EAE (days after start of treatment)

Max clinical score

Cumulative disease score

Vehicle

10

3.4 ± 0.6

2.6 ± 0.3

19.5 ± 4.3

RAM-589.555

10

2.3 ± 0.7

1.8 ± 0.3

10.7 ± 1.9

*p value

 

0.09

0.04

0.03

  1. * T test