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Table 2 Maturation onset (days) in healthy control and G6D-NAC2 groups

From: Systemic dendrimer-drug nanomedicines for long-term treatment of mild-moderate cerebral palsy in a rabbit model

Developmental milestone

Healthy control (n = 11)

G6D-NAC2 (n = 7)

Eye opening

10 (9, 10)***

13 (13, 14)

Body elevation

8 (7, 8)***

12 (11, 14)

Normal gait

8 (7, 8)***

12 (11, 13)

Head elevation

8 (7, 8)***

13 (11, 14)

Cessation of falling

7 (6, 7)***

13 (12, 15)

  1. Data were expressed as median (inter-quartile range). Body elevation, simultaneous fore- and hind-limb elevation; head elevation, head elevated for more than 1 min; cessation of falling, locomotion without falling. p values for other milestones were analyzed by one-way ANOVA (non-parametric)
  2. ***p < 0.0001, compared with G6D-NAC2 and G6D-NAC5