Fig. 6From: Sestrin2 regulates microglia polarization through mTOR-mediated autophagic flux to attenuate inflammation during experimental brain ischemiaSchematic of the neuroprotective role of sestrin2. After ischemia/hypoxia, sestrin2 promoted microglial polarization to M2 phenotype by restoring autophagic flux through mTOR pathway inhibition to prevent neuronal apoptosisBack to article page