Fig. 3

Ldlr knockout exacerbates long-term cognitive deterioration after stroke. a Representative swim path trace images of mice in hidden platform test (learning) and probe phase (memory). b, c The swim path length and escape latency were respectively detected at day 23–27 after reperfusion. d, e The percentage of time spent in the target quadrant and platform crossings were recorded at day 28 after reperfusion. Data are shown as mean ± SEM; n = 12 for all groups. *P < 0.05, **P < 0.01, ***P < 0.001 versus WT sham mice; ^#P < 0.05 versus WT MCAO mice