TY - JOUR AU - Ullah, F. AU - Ali, T. AU - Ullah, N. AU - Kim, M. O. PY - 2015 DA - 2015// TI - Caffeine prevents d-galactose-induced cognitive deficits, oxidative stress, neuroinflammation and neurodegeneration in the adult rat brain JO - Neurochem Int VL - 90 ID - Ullah2015 ER - TY - JOUR AU - Morrison, J. H. AU - Hof, P. R. PY - 1997 DA - 1997// TI - Life and death of neurons in the aging brain JO - Science VL - 278 ID - Morrison1997 ER - TY - JOUR AU - Raz, N. AU - Ghisletta, P. AU - Rodrigue, K. M. AU - Kennedy, K. M. AU - Lindenberger, U. PY - 2010 DA - 2010// TI - Trajectories of brain aging in middle-aged and older adults: regional and individual differences JO - Neuroimage VL - 51 ID - Raz2010 ER - TY - JOUR AU - Fiskum, G. AU - Rosenthal, R. E. AU - Vereczki, V. AU - Martin, E. AU - Hoffman, G. E. AU - Chinopoulos, C. AU - Kowaltowski, A. PY - 2004 DA - 2004// TI - Protection against ischemic brain injury by inhibition of mitochondrial oxidative stress JO - J Bioenerg Biomembr VL - 36 ID - Fiskum2004 ER - TY - JOUR AU - Ali, T. AU - Badshah, H. AU - Kim, T. H. AU - Kim, M. O. PY - 2015 DA - 2015// TI - Melatonin attenuates D-galactose-induced memory impairment, neuroinflammation and neurodegeneration via RAGE/NF-K B/JNK signaling pathway in aging mouse model JO - J Pineal Res VL - 58 ID - Ali2015 ER - TY - JOUR AU - Zhang, X. L. AU - Jiang, B. AU - Li, Z. B. AU - Hao, S. AU - An, L. J. PY - 2007 DA - 2007// TI - Catalpol ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by D-galactose JO - Pharmacol Biochem Behav VL - 88 ID - Zhang2007 ER - TY - JOUR AU - Cui, X. AU - Zuo, P. AU - Zhang, Q. AU - Li, X. AU - Hu, Y. AU - Long, J. AU - Packer, L. AU - Liu, J. PY - 2006 DA - 2006// TI - Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid JO - J Neurosci Res VL - 84 ID - Cui2006 ER - TY - JOUR AU - Kumar, A. AU - Prakash, A. AU - Dogra, S. PY - 2011 DA - 2011// TI - Centella asiatica attenuates D-galactose-induced cognitive impairment, oxidative and mitochondrial dysfunction in mice JO - Int J Alzheimers Dis VL - 2011 ID - Kumar2011 ER - TY - JOUR AU - Kumar, A. AU - Prakash, A. AU - Dogra, S. PY - 2011 DA - 2011// TI - Centella asiatica attenuates D-galactose-induced cognitive impairment, oxidative and mitochondrial dysfunction in mice JO - Int J Alzheimers Dis VL - 2011 ID - Kumar2011 ER - TY - JOUR AU - Lu, J. AU - Wu, D. M. AU - Zheng, Y. L. AU - Hu, B. AU - Zhang, Z. F. AU - Ye, Q. AU - Liu, C. M. AU - Shan, Q. AU - Wang, Y. J. PY - 2010 DA - 2010// TI - Ursolic acid attenuates D-galactose-induced inflammatory response in mouse prefrontal cortex through inhibiting AGEs/RAGE/NF-kappaB pathway activation JO - Cereb Cortex VL - 20 ID - Lu2010 ER - TY - JOUR AU - Liu, J. AU - Lin, A. PY - 2005 DA - 2005// TI - Role of JNK activation in apoptosis: a double-edged sword JO - Cell Res VL - 15 ID - Liu2005 ER - TY - JOUR AU - Maddux, B. A. AU - Grodsky, G. M. AU - Goldfine, I. D. AU - Evans, J. L. PY - 2002 DA - 2002// TI - Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes JO - Endocr Rev VL - 23 ID - Maddux2002 ER - TY - JOUR AU - Koch, P. AU - Gehringer, M. AU - Laufer, S. A. PY - 2015 DA - 2015// TI - Inhibitors of c-Jun N-terminal kinases: an update JO - J Med Chem VL - 58 ID - Koch2015 ER - TY - JOUR AU - Zhou, Q. AU - Wang, M. AU - Du, Y. AU - Zhang, W. AU - Bai, M. AU - Zhang, Z. AU - Li, Z. AU - Miao, J. PY - 2015 DA - 2015// TI - Inhibition of c-Jun N-terminal kinase activation reverses Alzheimer disease phenotypes in APPswe/PS1dE9 mice JO - Ann Neurol VL - 77 ID - Zhou2015 ER - TY - JOUR AU - Amin, F. U. AU - Shah, S. A. AU - Kim, M. O. PY - 2016 DA - 2016// TI - Glycine inhibits ethanol-induced oxidative stress, neuroinflammation and apoptotic neurodegeneration in postnatal rat brain JO - Neurochem Int VL - 96 ID - Amin2016 ER - TY - JOUR AU - Castillo, J. AU - Davalos, A. AU - Naveiro, J. AU - Noya, M. PY - 1996 DA - 1996// TI - Neuroexcitatory amino acids and their relation to infarct size and neurological deficit in ischemic stroke JO - Stroke VL - 27 ID - Castillo1996 ER - TY - JOUR AU - Gusev, E. I. AU - Skvortsova, V. I. AU - Dambinova, S. A. AU - Raevskiy, K. S. AU - Alekseev, A. A. AU - Bashkatova, V. G. AU - Kovalenko, A. V. AU - Kudrin, V. S. AU - Yakovleva, E. V. PY - 2000 DA - 2000// TI - Neuroprotective effects of glycine for therapy of acute ischaemic stroke JO - Cerebrovasc Dis VL - 10 ID - Gusev2000 ER - TY - STD TI - I.A k. Medicinal preparation of antistress, stress-protective and nootropic effect. United States: 1988. . ID - ref18 ER - TY - STD TI - Leeson PD, Iversen LL. The glycine site on the NMDA receptor: structure-activity relationships and therapeutic potential. J Med Chem. American Chemical Society (ACS); 1994;37:4053–67. https://pubs.acs.org/doi/10.1021/jm00050a001. UR - https://pubs.acs.org/doi/10.1021/jm00050a001 ID - ref19 ER - TY - JOUR AU - Johnson, J. AU - Ascher, P. PY - 1987 DA - 1987// TI - Glycine potentiates the NMDA response in cultured mouse brain neurons JO - Nature VL - 325 ID - Johnson1987 ER - TY - JOUR AU - Bannai, M. AU - Kawai, N. PY - 2012 DA - 2012// TI - New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep JO - J Pharmacol Sci VL - 118 ID - Bannai2012 ER - TY - JOUR AU - Shoham, S. AU - Javitt, D. C. AU - Heresco-Levy, U. PY - 2001 DA - 2001// TI - Chronic high-dose glycine nutrition: effects on rat brain cell morphology JO - Biol Psychiatry VL - 49 ID - Shoham2001 ER - TY - JOUR AU - Rehman, S. U. AU - Shah, S. A. AU - Ali, T. AU - Chung, J. I. AU - Kim, M. O. PY - 2017 DA - 2017// TI - Anthocyanins reversed D-Galactose-induced oxidative stress and neuroinflammation mediated cognitive impairment in adult rats JO - Mol Neurobiol VL - 54 ID - Rehman2017 ER - TY - JOUR AU - Shah, S. A. AU - Yoon, G. H. AU - Kim, M. O. PY - 2015 DA - 2015// TI - Protection of the developing brain with anthocyanins against ethanol-induced oxidative stress and neurodegeneration JO - Mol Neurobiol VL - 51 ID - Shah2015 ER - TY - STD TI - Muhammad T, Ikram M, Ullah R, Rehman SU, Kim MO. Hesperetin, a citrus flavonoid, attenuates LPS-induced neuroinflammation, apoptosis and memory impairments by modulating TLR4/NF-kappaB signaling. Nutrients. 2019;11(3):648. https://doi.org/10.3390/nu11030648. ID - ref25 ER - TY - JOUR AU - Khan, M. S. AU - Ali, T. AU - Kim, M. W. AU - Jo, M. H. AU - Chung, J. I. AU - Kim, M. O. PY - 2019 DA - 2019// TI - Anthocyanins improve hippocampus-dependent memory function and prevent neurodegeneration via JNK/Akt/GSK3beta signaling in LPS-treated adult mice JO - Mol Neurobiol VL - 56 ID - Khan2019 ER - TY - STD TI - Khan M, Rutten BPF, Kim MO. MST1 regulates neuronal cell death via JNK/Casp3 signaling pathway in HFD mouse brain and HT22 cells. Int J Mol Sci. 2019;20(10):2504; https://doi.org/10.3390/ijms20102504. ID - ref27 ER - TY - JOUR AU - Shah, S. A. AU - Lee, H. Y. AU - Bressan, R. A. AU - Yun, D. J. AU - Kim, M. O. PY - 2014 DA - 2014// TI - Novel osmotin attenuates glutamate-induced synaptic dysfunction and neurodegeneration via the JNK/PI3K/Akt pathway in postnatal rat brain JO - Cell Death Dis VL - 5 ID - Shah2014 ER - TY - STD TI - Molecular Operating Environment (MOE), 2016.08; Chemical computing group Inc., 1010 Sherbrooke St. West, Suite #910, Montreal, QC, Canada, H3A 2R7,. 2016. ID - ref29 ER - TY - JOUR AU - Badshah, H. AU - Ali, T. AU - Kim, M. O. PY - 2016 DA - 2016// TI - Osmotin attenuates LPS-induced neuroinflammation and memory impairments via the TLR4/NFkappaB signaling pathway JO - Sci Rep VL - 6 ID - Badshah2016 ER - TY - JOUR AU - Badshah, H. AU - Kim, T. H. AU - Kim, M. J. AU - Ahmad, A. AU - Ali, T. AU - Yoon, G. H. AU - Naseer, M. I. AU - Kim, M. O. PY - 2014 DA - 2014// TI - Apomorphine attenuates ethanol-induced neurodegeneration in the adult rat cortex JO - Neurochem Int VL - 74 ID - Badshah2014 ER - TY - JOUR AU - Cui, X. AU - Zuo, P. AU - Zhang, Q. AU - Li, X. AU - Hu, Y. AU - Long, J. AU - Packer, L. AU - Liu, J. PY - 2006 DA - 2006// TI - Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid JO - J Neurosci Res VL - 83 ID - Cui2006 ER - TY - JOUR AU - Lu, J. AU - Zheng, Y. L. AU - Wu, D. M. AU - Luo, L. AU - Sun, D. X. AU - Shan, Q. PY - 2007 DA - 2007// TI - Ursolic acid ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by D-galactose JO - Biochem Pharmacol VL - 74 ID - Lu2007 ER - TY - JOUR AU - Li, P. AU - Nijhawan, D. AU - Budihardjo, I. AU - Srinivasula, S. M. AU - Ahmad, M. AU - Alnemri, E. S. AU - Wang, X. PY - 1997 DA - 1997// TI - Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade JO - Cell VL - 91 ID - Li1997 ER - TY - JOUR AU - Thornberry, N. A. AU - Lazebnik, Y. PY - 1998 DA - 1998// TI - Caspases: enemies within JO - Science VL - 281 ID - Thornberry1998 ER - TY - JOUR AU - Lu, J. AU - Dm, W. AU - Yl, Z. AU - Hu, B. AU - Zf, Z. PY - 2010 DA - 2010// TI - Purple sweet potato color alleviates d-galactose-induced brain aging in old mice by promoting survival of neurons via PI3K pathway and inhibiting cytochrome c-mediated apoptosis JO - Brain Pathol VL - 20 ID - Lu2010 ER - TY - JOUR AU - Manning, A. M. AU - Davis, R. J. PY - 2003 DA - 2003// TI - Targeting JNK for therapeutic benefit: from junk to gold? JO - Nat Rev Drug Discov VL - 2 ID - Manning2003 ER - TY - JOUR AU - Salminen, A. AU - Ojala, J. AU - Kauppinen, A. AU - Kaarniranta, K. AU - Suuronen, T. PY - 2009 DA - 2009// TI - Inflammation in Alzheimer's disease: amyloid-beta oligomers trigger innate immunity defence via pattern recognition receptors JO - Prog Neurobiol VL - 87 ID - Salminen2009 ER - TY - JOUR AU - Wu, D. M. AU - Lu, J. AU - Zheng, Y. L. AU - Zhou, Z. AU - Shan, Q. AU - Ma, D. F. PY - 2008 DA - 2008// TI - Purple sweet potato color repairs d-galactose-induced spatial learning and memory impairment by regulating the expression of synaptic proteins JO - Neurobiol Learn Mem VL - 90 ID - Wu2008 ER - TY - STD TI - Repici M, Borsello T. JNK pathway as therapeutic target to prevent degeneration in the central nervous system. In: Hypoxia and Exercise. Springer Nature Switzerland AG: Springer; 2006. p. 145–55. ID - ref40 ER - TY - JOUR AU - Chen, X. AU - Guo, C. AU - Kong, J. PY - 2012 DA - 2012// TI - Oxidative stress in neurodegenerative diseases JO - Neural Regen Res VL - 7 ID - Chen2012 ER - TY - JOUR AU - Parameshwaran, K. AU - Irwin, M. H. AU - Steliou, K. AU - Pinkert, C. A. PY - 2010 DA - 2010// TI - D-galactose effectiveness in modeling aging and therapeutic antioxidant treatment in mice JO - Rejuvenation Res VL - 13 ID - Parameshwaran2010 ER - TY - JOUR AU - Ramsey, C. P. AU - Glass, C. A. AU - Montgomery, M. B. AU - Lindl, K. A. AU - Ritson, G. P. AU - Chia, L. A. AU - Hamilton, R. L. AU - Chu, C. T. AU - Jordan-Sciutto, K. L. PY - 2007 DA - 2007// TI - Expression of Nrf2 in neurodegenerative diseases JO - J Neuropathol Exp Neurol VL - 66 ID - Ramsey2007 ER - TY - JOUR AU - Shah, S. A. AU - Khan, M. AU - Jo, M. H. AU - Jo, M. G. AU - Amin, F. U. AU - Kim, M. O. PY - 2017 DA - 2017// TI - Melatonin stimulates the SIRT1/Nrf2 signaling pathway counteracting lipopolysaccharide (LPS)-induced oxidative stress to rescue postnatal rat brain JO - CNS Neurosci Ther VL - 23 ID - Shah2017 ER - TY - JOUR AU - Cargnello, M. AU - Roux, P. P. PY - 2011 DA - 2011// TI - Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases JO - Microbiol Mol Biol Rev VL - 75 ID - Cargnello2011 ER - TY - JOUR AU - Broom, O. J. AU - Widjaya, B. AU - Troelsen, J. AU - Olsen, J. AU - Nielsen, O. H. PY - 2009 DA - 2009// TI - Mitogen activated protein kinases: a role in inflammatory bowel disease? JO - Clin Exp Immunol VL - 158 ID - Broom2009 ER - TY - JOUR AU - Aoki, K. AU - Yamada, M. AU - Kunida, K. AU - Yasuda, S. AU - Matsuda, M. PY - 2011 DA - 2011// TI - Processive phosphorylation of ERK MAP kinase in mammalian cells JO - Proc Natl Acad Sci U S A VL - 108 ID - Aoki2011 ER - TY - JOUR AU - Zhu, X. AU - Raina, A. K. AU - Lee, H. G. AU - Casadesus, G. AU - Smith, M. A. AU - Perry, G. PY - 2004 DA - 2004// TI - Oxidative stress signalling in Alzheimer's disease JO - Brain Res VL - 1000 ID - Zhu2004 ER - TY - JOUR AU - Johnson, G. L. AU - Nakamura, K. PY - 1773 DA - 1773// TI - The c-jun kinase/stress-activated pathway: regulation, function and role in human disease JO - Biochim Biophys Acta VL - 2007 ID - Johnson1773 ER - TY - JOUR AU - Ma, Y. AU - Ma, B. AU - Shang, Y. AU - Yin, Q. AU - Wang, D. AU - Xu, S. AU - Hong, Y. AU - Hou, X. AU - Liu, X. PY - 2018 DA - 2018// TI - Flavonoid-rich ethanol extract from the leaves of diospyros kaki attenuates D-galactose-induced oxidative stress and neuroinflammation-mediated brain aging in mice JO - Oxidative Med Cell Longev VL - 2018 ID - Ma2018 ER - TY - JOUR AU - Zhang, J. AU - Dawson, V. L. AU - Dawson, T. M. AU - Snyder, S. H. PY - 1994 DA - 1994// TI - Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity JO - Science VL - 263 ID - Zhang1994 ER - TY - JOUR AU - Rehman, S. U. AU - Ahmad, A. AU - Yoon, G. H. AU - Khan, M. AU - Abid, M. N. AU - Kim, M. O. PY - 2018 DA - 2018// TI - Inhibition of c-Jun N-Terminal Kinase Protects Against Brain Damage and Improves Learning and Memory After Traumatic Brain Injury in Adult Mice JO - Cereb Cortex VL - 28 ID - Rehman2018 ER - TY - JOUR AU - Tournier, C. AU - Hess, P. AU - Yang, D. D. AU - Xu, J. AU - Turner, T. K. AU - Nimnual, A. AU - Bar-Sagi, D. AU - Jones, S. N. AU - Flavell, R. A. AU - Davis, R. J. PY - 2000 DA - 2000// TI - Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway JO - Science VL - 288 ID - Tournier2000 ER - TY - JOUR AU - Parsons, C. AU - Danysz, W. AU - Hesselink, M. AU - Hartmann, S. AU - Lorenz, B. AU - Wollenburg, C. AU - Quack, G. PY - 1998 DA - 1998// TI - Modulation of NMDA receptors by glycine—introduction to some basic aspects and recent developments JO - Amino Acids VL - 14 ID - Parsons1998 ER - TY - JOUR AU - Hu, R. AU - Chen, J. AU - Lujan, B. AU - Lei, R. AU - Zhang, M. AU - Wang, Z. AU - Liao, M. AU - Li, Z. AU - Wan, Y. AU - Liu, F. PY - 2016 DA - 2016// TI - Glycine triggers a non-ionotropic activity of GluN2A-containing NMDA receptors to confer neuroprotection JO - Sci Rep VL - 6 ID - Hu2016 ER - TY - JOUR AU - Dhanasekaran, D. N. AU - Reddy, E. P. PY - 2008 DA - 2008// TI - JNK signaling in apoptosis JO - Oncogene VL - 27 ID - Dhanasekaran2008 ER - TY - JOUR AU - Daniele, S. AU - Zappelli, E. AU - Martini, C. PY - 2015 DA - 2015// TI - Trazodone regulates neurotrophic/growth factors, mitogen-activated protein kinases and lactate release in human primary astrocytes JO - J Neuroinflammation VL - 12 ID - Daniele2015 ER - TY - STD TI - Tang H, Dai Q, Hong W, Han K, Jia D, Mo Y, Lv Y, Fu H, Zheng J, Geng W. JNK-IN-8, a c-Jun N-terminal kinase inhibitor, improves functional recovery through suppressing neuroinflammation in ischemic stroke. bioRxiv. 2018; 235:449496. ID - ref58 ER - TY - JOUR AU - Sanada, F. AU - Taniyama, Y. AU - Muratsu, J. AU - Otsu, R. AU - Shimizu, H. AU - Rakugi, H. AU - Morishita, R. PY - 2018 DA - 2018// TI - Source of Chronic Inflammation in Aging JO - Front Cardiovasc Med VL - 5 ID - Sanada2018 ER - TY - JOUR AU - Akiyama, H. AU - Barger, S. AU - Barnum, S. AU - Bradt, B. AU - Bauer, J. AU - Cole, G. M. AU - Cooper, N. R. AU - Eikelenboom, P. AU - Emmerling, M. AU - Fiebich, B. L. PY - 2000 DA - 2000// TI - Inflammation and Alzheimer's disease JO - Neurobiol Aging VL - 21 ID - Akiyama2000 ER - TY - JOUR AU - Mehan, S. AU - Meena, H. AU - Sharma, D. AU - Sankhla, R. PY - 2011 DA - 2011// TI - JNK: a stress-activated protein kinase therapeutic strategies and involvement in Alzheimer's and various neurodegenerative abnormalities JO - J Mol Neurosci VL - 43 ID - Mehan2011 ER - TY - JOUR AU - Liu, R. AU - Liu, I. Y. AU - Bi, X. AU - Thompson, R. F. AU - Doctrow, S. R. AU - Malfroy, B. AU - Baudry, M. PY - 2003 DA - 2003// TI - Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics JO - Proc Natl Acad Sci U S A VL - 100 ID - Liu2003 ER - TY - JOUR AU - Tang, Y. AU - Xu, A. AU - Shao, S. AU - Zhou, Y. AU - Xiong, B. AU - Li, Z. PY - 2020 DA - 2020// TI - Electroacupuncture ameliorates cognitive impairment by inhibiting the JNK signaling pathway in a mouse model of Alzheimer’s disease JO - Front Aging Neurosci VL - 12 ID - Tang2020 ER - TY - JOUR AU - Wei, H. AU - Li, L. AU - Song, Q. AU - Ai, H. AU - Chu, J. AU - Li, W. PY - 2005 DA - 2005// TI - Behavioural study of the D-galactose induced aging model in C57BL/6J mice JO - Behav Brain Res VL - 157 ID - Wei2005 ER - TY - JOUR AU - Shwe, T. AU - Pratchayasakul, W. AU - Chattipakorn, N. AU - Chattipakorn, S. C. PY - 2018 DA - 2018// TI - Role of D-galactose-induced brain aging and its potential used for therapeutic interventions JO - Exp Gerontol VL - 101 ID - Shwe2018 ER -